The prevalence of chronic pain varies, but according to CDC estimates, 14.6 percent of adults in the United States have current widespread or localized pain lasting at least three months.
Treatments for chronic pain are inadequate, and new options are needed. Nonpharmaceutical approaches are especially attractive with many potential advantages, including safety.
The effects of the green LED lasted for four days after the rats’ last exposure to the light. There were no side effects from the green LED therapy, and there was no tolerance to the therapy.
“Chronic pain is a serious issue afflicting millions of people of all ages,” says Mohab Ibrahim, UA assistant professor of Anesthesiology and Pharmacology and lead author of the study. “Pain physicians are trained to manage chronic pain in several ways including medication and interventional procedures in a multimodal approach. Opioids, while having many benefits for managing pain, come with serious side effects. We need safer, effective and affordable approaches, used in conjunction with our current tools, to manage chronic pain. While the results of the green LED are still preliminary, it holds significant promise to manage some types of chronic pain.”
To receive the green LED exposure, one group of rats were placed in clear plastic containers that were affixed with green LED strips, allowing them to be bathed in green light. Another group of rats was exposed to room light and fitted with contact lenses that allowed the green spectrum wavelength to pass through. Both groups benefitted from the green LED exposure. However, another group of rats was fitted with opaque contact lenses, which blocked the green light from entering their visual system. These rats did not benefit from the green LED exposure.
“While the pain-relieving qualities of green LED are clear, exactly how it works remains a puzzle,” says Rajesh Khanna, UA associate professor of Pharmacology and senior author of the study. “Early studies show that green light is increasing the levels of circulating endogenous opioids, which may explain the pain-relieving effects. Whether this will be observed in humans is not yet known and needs further work.”
researchers are now conducting a small, randomized, double-blind clinical trial to study the effects of green LED light on people with fibromyalgia, a common source of chronic pain. Participants are provided with a green LED light strip to use in a darkened room for one to two hours nightly for 10 weeks.
Source : Article Compiled from different source
Green Light LED Being Tested to Treat Chronic Pain and Fibromyalgia retrieved from National Pain Report
University of Arizona. “Promise in light therapy to treat chronic pain.” ScienceDaily. ScienceDaily, 28 February 2017. <www.sciencedaily.com/releases/2017/02/170228185325.htm>
- Mohab M. Ibrahim, Amol Patwardhan, Kerry B. Gilbraith, Aubin Moutal, Xiaofang Yang, Lindsey A. Chew, Tally Largent-Milnes, T. Philip Malan, Todd W. Vanderah, Frank Porreca, Rajesh Khanna. Long-lasting antinociceptive effects of green light in acute and chronic pain in rats. PAIN, 2017; 158 (2): 347 DOI: